Mod GRF 1-29

Mod GRF 1-29 is a modified version of GRF 1-29 (hence mod), being a second generation growth hormone secretagogue, or growth hormone releasing hormone (GHRH). It is sometimes known as CJC1295 without Dac, as CJC1295dac underwent further modification of this peptide to increase the active life and duration significantly. So, technically speaking calling it CJC1295 without Dac is a mistake in naming, simply because it was around before the creation of the third-generation CJC1295dac.

Being a growth hormone secretagogue, it merely enhances natural growth hormone pulses, and is less oppressive of endogenous production than synthetic HGH is. The name Mod GRF 1-29 is indicative of the amino acid chain length of the analog, which comes in at 29, compared to natural GHRH at 44.

Effects of MOD GRF 1-29

Effects of Mod GRF 1-29 are synonymous with human growth hormone, with the exception that it is amplified several-fold. It promotes a state of positive nitrogen balance, increases lipolytic activity, and supports structural regeneration and recovery of connective soft tissue types.

Though rarely used for this purpose, it is also sometimes sought out to improve the overall appearance of skin with or without a GHRP.

MOD GRF 1-29 Pharmacology

Mod GRF 1-29 stimulates the pituitary gland to significantly increase output of growth hormone during normal pulsatile secretion patterns. The magnitude of its effects are comparable to exogenous HGH administration, and as such when used over long periods of time can be suppressive to natural production. It is sometimes combined with a potent GHRP such as GHRP-6 which stimulates a massive release of ghrelin, in turn amplifying the magnitude of growth hormone release from the pituitary.

MOD GRF 1-29 Dosage

The exact dosage and frequency of administration of Mod GRF 1-29 can vary depending on factors such as if you are looking for an antiaging solution, recovery and recuperation, fat loss or muscle gain. Typical dosages are in the vicinity of 100 µg administered at a minimum of twice daily, and increased to a maximum of five times daily separated by a minimum of three hours from adjacent injections.

With the duration of action coming in at approximately 30 minutes, it is the best choice for taking advantage of growth hormone’s natural pulsatile spikes. Natural GHRH has a duration of action of just 10 minutes, which is too short to elicit maximal effect.

All cycles typically last for a period of 4 to 6 months after which it is usually stopped to prevent endogenous hormone shutdown.

Possible Adverse Effects Of MOD GRF 1-29

  • Hypoglycemia – a recurring theme with many growth hormone secretagogues as a result of impaired glucose metabolism in favor of fatty acid utilization.
  • Accelerated tumor growth in susceptible people
  • Nerve compression, or carpal tunnel syndrome
  • Occasionally, localized tingling in areas of administration


The short duration of action makes it ideal for taking advantage of pulsatile releases of HGH, being particularly suited for athletic disciplines. It is less suitable for general health or antiaging, as these goals do not require you take maximum advantage of natural spikes in release. CJC1295dac is a superior alternative for these people.

Mod GRF 1-29 is also much safer than exogenous HGH administration and much more cost-effective over the long haul.